The rise of longevity care in America, in numbers

Americans are looking for it

Until 2022, "longevity clinic" barely registered on Google. That changed in 2022, and the climb has steepened every year since. In 2026, US searches for "longevity clinic" are running about 19 times their 2021 level. Searches for "longevity doctor" and "full-body MRI" have followed the same path.

Surveys back this up. In a 2025 Pew Research survey of 8,750 US adults, Americans said they would like to live to 91 on average, and 29% said they would like to reach 100. In McKinsey’s 2025 Future of Wellness survey, up to 60% of consumers called healthy aging a top or very important priority.

A few public figures carried these ideas to a mass audience. Physician Peter Attia’s book Outlive (2023) became a No. 1 New York Times bestseller, with more than 2 million copies sold, according to its publisher. Entrepreneur Bryan Johnson’s anti-aging routine was the subject of a Netflix documentary, Don’t Die, in January 2025. Neuroscientist Andrew Huberman’s podcast, Huberman Lab, was the No. 9 show on Apple Podcasts in the US in 2025. All three have also drawn criticism, from scientists questioning overstated claims to reporting on their businesses and conduct.

The country is also getting older. The number of Americans aged 65 and up grew 13% from 2020 to 2024, to 61.2 million, and the number of US metro areas where older adults outnumber children nearly doubled, from 58 to 112, according to the Census Bureau.

The press has noticed

News coverage tells the same story. US online news articles that mention longevity clinics went from 26 in 2023 to 105 in 2025, and 2026 had already passed that by September. Over the same years, the news database we used tracked fewer articles overall, so longevity clinics are taking up a much bigger share of coverage.

Clinics are opening fast, and chains are leading

We track 903 longevity clinics across 40 US metros. To see how fast they are appearing, we researched when each clinic opened in seven of the biggest markets: New York, Miami, Boston, Los Angeles, San Francisco, Chicago and Dallas. We found a solid opening date for 111 of 237 clinics, using state business records first, then the clinic’s own history, then news coverage.

Nearly half of those clinics opened in 2020 or later, and nearly a third opened since 2023. The biggest change is who is opening them. Before 2020, chains and franchises made up 8% of new openings. Since 2020, they make up 44%.

The chain numbers show the speed. Restore Hyper Wellness grew from 21 locations in 2019 to more than 225 by early 2024. Next Health went from 5 locations at the end of 2024 to about 19 by mid-2026. Neko Health, co-founded by Spotify’s Daniel Ek, opened its first US clinic in New York in September 2026, with more than 25,000 New Yorkers already on its waitlist.

Big-name hospitals are opening longevity clinics too

This is not only a startup trend. Some of the best-known medical centers in the country now run their own longevity clinics, led by senior physicians and researchers. In October 2026, STAT News reported that "Northwestern Medicine, Weill Cornell, and Mayo Clinic have all launched cash-pay longevity clinics." Patients typically pay out of pocket, since insurance doesn’t cover these programs.

Academic medicine shows up in our own data too. In Boston, 5 of the 30 clinics we list are led by doctors with Mass General Brigham or Beth Israel Deaconess and Harvard Medical School affiliations. Other systems, including Mayo, Cleveland Clinic and Mass General Brigham, have long run executive health programs that offer many of the same tests, even if they don’t use the word longevity.

Growth is not straight up. Restore, which grew fastest, has held at about 220 locations since 2024, and Next Health is well behind its earlier target of 150 locations by 2027.

What these clinics actually offer

Across all 903 clinics we track, the most common offers are IV vitamin therapy, hormone therapy, peptide therapy and NAD+ therapy. About one in 13 offers a biological age test.

What these tests are, in plain English

Explainer Full-body MRI

A radiation-free scan that looks for tumors, aneurysms and other problems before symptoms. Offered by about 1 in 6 clinics.

Explainer DEXA scan

Measures your fat, muscle and bone, including the fat around your organs.

Explainer VO2 max test

Measures your fitness at full effort, one of the strongest signs of a long life.

Reference Blood biomarker panels

Dozens of markers, from ApoB to vitamin D, well beyond a standard checkup.

Explainer Biological age tests

Estimate how fast your body is aging, from your DNA or blood.

Explainer Baseline testing

How these tests fit together into a starting point, and when to retest.

Tests are getting cheaper

Technology and competition are pulling prices down for some of the headline tests. Ezra’s full-body MRI cost $1,950 for an hour-long scan in 2019, $1,350 for a 30-minute scan in 2023, and $499 for Function Health members in 2025, after FDA-cleared AI image enhancement cut the scan to about 22 minutes. Function’s yearly membership for 160+ blood tests fell from $499 to $365 in November 2025, and Superpower lists $199 a year for 100+. A coronary calcium scan that cost $395 in 1998 is now under $100 in many US cities, with some hospitals charging $49.

Not everything is falling. Prenuvo’s whole-body scan is still $2,499, as it was in 2023. DEXA body scans haven’t followed either: at the 32 clinics we track that publish a price, a DEXA scan costs $65 to $249, typically about $140, and we found no good record showing that has dropped. And much of the fall in calcium scan prices came before the longevity boom: hospitals were already running $49 promotions in 2013.

The money is following

Investment into longevity companies more than doubled from 2023 to 2024, to $8.5 billion, according to Longevity.Technology. Some of the best-known names in tech and business are among the backers.

The science is speeding up

The research behind longevity care is growing much faster than science as a whole. From 2015 to 2025, studies on senolytics went from 13 to more than 1,600. Senolytics are drugs designed to clear out worn-out "zombie" cells, which build up as we age and inflame the tissue around them. Studies on epigenetic clocks, tests that estimate your body’s age from your DNA, went from 49 to 1,070, and studies on biological age from 269 to 2,222. Medical research overall grew about 1.5 times.

More of that research is moving into people. New clinical trials built around aging itself, using terms like biological age, senolytics or healthspan (the years you live in good health), rose from 8 in 2015 to 71 in 2025.

AI is speeding up the research

Artificial intelligence is starting to compress the slowest parts of drug discovery. A few examples:

• An AI-designed drug for an age-related disease reached late-stage trials. Insilico Medicine used AI to find both the target and the molecule for rentosertib, a drug for lung scarring that its researchers call an age-related disease. It went from target to drug candidate in about 18 months, showed improved lung function in a 71-patient trial published in Nature Medicine in 2025, and began a 320-patient Phase 3 trial in July 2026.
• AI redesigned the proteins used to rejuvenate cells. OpenAI and Retro Biosciences reported in 2025 that AI-designed versions of two "reprogramming" proteins worked more than 50 times better in lab tests than the natural versions. The work has not yet been peer-reviewed.
• Old livers acting younger, in mice. NewLimit, the company co-founded by Coinbase’s Brian Armstrong, reported in July 2026 that old mice normally sleep for hours after drinking alcohol, while old mice given its liver "reprogramming" treatment behaved more like young mice. It is a company update without published numbers yet. NewLimit plans its first human trial in 2027.
• AI found new drugs that clear worn-out cells. Researchers at MIT and Integrated Biosciences used AI to screen more than 800,000 molecules and found three new compounds that clear worn-out cells, one of which worked in aged mice (Nature Aging, 2023).
• Years of lab work in months. Harvard geneticist David Sinclair said on The Joe Rogan Experience in August 2026 that an AI-powered screen his team ran "in a couple of months would have taken about 160 years to complete." That is his own estimate, and the work has not been published yet.

AlphaFold, the AI system whose creators shared the 2024 Nobel Prize in Chemistry, has predicted the shapes of about 200 million proteins, compared with about 190,000 solved by lab methods over 60 years. Much of this new work builds on that foundation.

Public funding has grown too. The National Institute on Aging’s budget roughly quadrupled from 2010 to 2025; over the same years, Congress added dedicated funding for Alzheimer’s research.

Milestones in aging science

1. 2009Rapamycin becomes the first drug shown to extend lifespan in mammals, even when started late in life in mice
2. 2013Scientists publish the first "epigenetic clocks" and the "Hallmarks of Aging", which becomes the field’s map
3. 2015The first senolytic drugs are named: compounds that clear worn-out "zombie" cells
4. 2016Brief genetic "reprogramming" reverses signs of aging in mice
5. 2018 to 2022Newer clocks (PhenoAge, GrimAge, DunedinPACE) predict health and the pace of aging, not just birthdays
6. 2022Altos Labs launches with $3 billion
7. 2023Blood tests estimate the age of 11 organs separately. The "Hallmarks" grow from 9 to 12. The $101 million XPRIZE Healthspan launches
8. 2026The US government’s ARPA-H awards up to $144 million to seven "healthspan" teams. XPRIZE names 20 finalists. A dog longevity drug has cleared 2 of the 3 technical sections the FDA requires for conditional approval

Beyond the clinic

The same demand shows up well outside longevity clinics:

• Wearables. Oura says it has sold more than 5.5 million rings since 2015, over half of them in the year to September 2025, and that revenue topped $500 million in 2024, double the year before.
• Employers. 43% of US employers with 5,000 or more workers covered GLP-1 drugs for weight loss in 2025, up from 28% in 2024 (KFF). Life insurer John Hancock began offering eligible customers $500 off a Prenuvo full-body MRI in 2024.
• Doctors. More than 8,000 healthcare practitioners attended a single longevity medicine conference in Las Vegas in 2024 (A4M). A lifestyle medicine curriculum is now available to 368 residency programs (American College of Lifestyle Medicine, 2024).

What hasn’t changed

For all the momentum, aging itself is still not a recognized medical condition. The FDA has never approved a drug to treat aging, and no measure of biological age is accepted as proof that a treatment works. The largest planned human trial of an aging drug, TAME, was designed in 2016 and still had not started by 2026. Many services offered at longevity clinics are early-stage, and longevity care works best alongside your regular doctor, not instead of them.

The business is harder than the headlines suggest. In a 2025 survey of 82 longevity clinics worldwide, 77% planned to expand, but only 39% said they were profitable (Longevity.Technology). Medical groups are also cautious: the American College of Radiology says there is not enough evidence to recommend full-body MRI screening for people without symptoms or risk factors. And regulators are watching. In 2026 the FDA warned a supplier after three patients were sent to the emergency room following compounded NAD+ from a single vial, and it has flagged dosing errors of 5 to 20 times the intended amount with compounded semaglutide.

About this data

Clinic openings. We researched 237 clinics in seven metros, in October 2026. For each one we looked for the state business registration, the clinic’s own stated founding year and news coverage, and recorded a confidence level. We use the year a location opened, never the year its brand was founded. We count 111 clinics with high or medium confidence. We only see clinics open today; clinics that opened and closed earlier are missing, which can make recent growth look larger. Dating was easier in some states than others. California business records were looked up by hand in October 2026, and some LA and SF clinics, mostly chain locations, still have no solid date.

Search interest is from Google Trends (US), where each term is scaled to its own peak. News counts are from the GDELT Project. Studies are counts of PubMed records by year via Europe PMC. Trials are keyword counts on ClinicalTrials.gov by start year. Investment and company figures are from the sources linked.

Directory figures (the 903 clinics, 40 metros, the services chart and the DEXA price) are computed from our directory each time the page is built. Directory figures as of November 2026. Hand-researched facts keep their own dates.

Download: clinic opening data (CSV) · all chart data (CSV)

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