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Indianapolis · Guide · Advanced and emerging treatments

Advanced and emerging treatments in Indianapolis

Treatments at the experimental edge of longevity care. Here's what each one is, what the evidence says, and which Indianapolis clinics offer them.

Main treatments
Peptides, NAD+ and hyperbaric oxygen Plus plasma exchange, stem cells and PRP
What you do
Ask what it's for, and for the evidence Then ask about safety
You get
A date to judge whether it helped If you decide to go ahead
Indianapolis photograph by Ryan De Hamer · Unsplash

The treatments, in plain English

These treatments sit at the experimental edge of longevity care. A few have real but narrow medical uses, like hyperbaric oxygen for hard-to-heal wounds. For aging itself, the evidence is thin, and some carry real risks. Go in with clear questions, and be wary of big promises.

Think of these like new restaurants with no reviews yet. Some may turn out great, but right now you're mostly going on the chef's word.

Peptide therapy

Short chains of amino acids, often injected, sold for recovery, sleep or muscle. Most are not FDA-approved for these uses, and the FDA has flagged some as possible safety risks.

NAD+ therapy

An IV drip or shot of a molecule your cells use to make energy. Human studies so far are small and short, so the benefit for aging is unclear.

Cash price: $36 to $800

Hyperbaric oxygen

Breathing pure oxygen in a pressurized chamber. An established hospital treatment for things like carbon monoxide poisoning, the bends and hard-to-heal wounds. Anti-aging uses fall outside that list.

Therapeutic plasma exchange

Removes and replaces the liquid part of your blood. A standard hospital treatment for certain blood, nerve and immune diseases. Using it for aging is early research.

Ozone and blood filtration

Mixing ozone into your blood, or filtering it, for a "detox". The FDA describes ozone as a toxic gas with no known useful medical use.

Stem cells and exosomes

The only FDA-approved stem cell products are cord-blood cells for certain blood disorders, and no exosome products are approved. Treatments sold for aging, joints or the brain are unapproved.

PRP injections

Your own blood, spun to concentrate platelets, then injected into a joint, tendon or skin. Some support for tennis elbow and knee arthritis, little for most other uses.

Prices that clinics publish on their own websites, across all the cities we cover. Prices change, so confirm with the clinic.

Showing 6 clinics that publish advanced and emerging care in Indianapolis

How we order clinics
Annamarie Salyer, BionwoRx: Center for Functional and Regenerative Medicine

BionwoRx: Center for Functional and Regenerative Medicine

N Pennsylvania St, Carmel
Advanced diagnostics & emerging careGenetics & biological ageHormones & energy

BionwoRx is a functional and regenerative medicine clinic on N Pennsylvania St in Carmel, founded by Annamarie Salyer, a family nurse practitioner. It offers functional lab testing, including hormone panels, micronutrient and telomere testing, alongside bioidentical hormone therapy, men's TRT, NAD+ therapy, peptide therapy and IV vitamins. Its regenerative menu adds PRP, A2M, EBO2 ozone and light therapies.

Tests & services

Hormone panel Peptide therapy IV vitamin therapy Blood-filtration therapy +9 more
See if it’s a fit
Mara WattamHannah Croffie

Defy of Indiana

W Carmel Dr, Carmel
Advanced diagnostics & emerging careStrength, fitness & body compositionHormones & energy

Defy of Indiana is a functional medicine practice on W Carmel Dr in Carmel. It offers bioidentical hormone replacement for men and women, including BioTE, alongside peptide therapy, gut and digestive health care, weight loss support and InBody body composition testing, with esthetic treatments such as Dysport and IPL. Care is direct pay per visit, with no membership required.

Tests & services

Peptide therapy Bioimpedance body composition Botox & fillers IV vitamin therapy +3 more
See if it’s a fit
Dr. Simranjit SinghDr. Sanna Singh

The Functional MDs

Executive Dr, Carmel
Advanced diagnostics & emerging careStrength, fitness & body compositionHormones & energy

The Functional MDs is a functional medicine practice on Executive Dr in Carmel, run by Dr. Simranjit Singh and Dr. Sanna Singh, both published as board-certified in internal medicine and obesity medicine. It offers hormone optimization, peptide therapy and longevity care. Its concierge primary care membership includes an annual assessment with advanced labs, VO2 max testing and body composition. Led by Dr. Simranjit Singh, MD, Dr. Sanna Singh, MD.

Tests & services

Peptide therapy VO₂ max testing
See if it’s a fit
Treatment studio

Prime IV Hydration & Wellness Carmel-The Bridges

Springmill Road, Carmel
3 locations, also in Greenwood and Zionsville
Advanced diagnostics & emerging careSleep, stress & recovery

Prime IV Hydration & Wellness Carmel-The Bridges is an IV hydration and wellness spa on Springmill Road in Carmel, one of the Prime IV Hydration & Wellness franchise locations. Its location page lists IV drips, vitamin injections and NAD+ infusions in 500mg and 1000mg doses. It also lists a Weight Loss Program. Clients sit in massage chairs during treatment.

Tests & services

IV vitamin therapy NAD+ therapy
See if it’s a fit
Treatment studio

Prime IV Hydration & Wellness Greenwood

South State Road 135, Greenwood
3 locations, also in Carmel and Zionsville
Advanced diagnostics & emerging careSleep, stress & recovery

Prime IV Hydration & Wellness Greenwood is an IV hydration and wellness spa on South State Road 135 in Greenwood, one of the Prime IV Hydration & Wellness franchise locations. Its location page lists IV drips, vitamin injections and NAD+ infusions in 500mg and 1000mg doses. It also lists a Weight Loss Program. Clients sit in massage chairs during treatment.

Tests & services

IV vitamin therapy NAD+ therapy
See if it’s a fit
Treatment studio

Prime IV Hydration & Wellness Zionsville - The Farm

Sylo Crossing, Zionsville
3 locations, also in Carmel and Greenwood
Advanced diagnostics & emerging careSleep, stress & recovery

Prime IV Hydration & Wellness Zionsville - The Farm is an IV hydration and wellness spa on Sylo Crossing in Zionsville, one of the Prime IV Hydration & Wellness franchise locations. Its location page lists IV drips, vitamin injections and NAD+ infusions in 500mg and 1,000mg doses. Clients sit in massage chairs during treatment.

Tests & services

IV vitamin therapy NAD+ therapy
See if it’s a fit

How to approach these treatments

  1. Ask what it is for

    The exact goal, and what result would count as it working.

  2. Ask for the evidence

    Which studies support it, and in people like you.

  3. Ask about safety

    Who makes the product, the side effects, and who handles problems.

  4. Track it

    If you go ahead, set a date to judge whether it actually helped.

If you have a serious condition, don't swap proven treatment for any of these.

Go deeper

Common questions

Which clinics in Indianapolis publish advanced and emerging care?

6 in our Indianapolis guide: BionwoRx: Center for Functional and Regenerative Medicine, Defy of Indiana, The Functional MDs, Prime IV Hydration & Wellness Carmel-The Bridges, Prime IV Hydration & Wellness Greenwood and Prime IV Hydration & Wellness Zionsville - The Farm.

Are these treatments FDA-approved?

Mostly not for longevity. Hyperbaric oxygen and plasma exchange are standard hospital treatments for specific conditions. The FDA has approved no exosome products, and only cord-blood stem cells for certain blood disorders.

Are peptides safe?

It depends on the peptide and who makes it. Most aren't approved for the uses clinics sell them for, and the FDA lists some as possible safety risks in compounded drugs. Ask exactly which peptide, where it's made, and what side effects to watch for.

Does NAD+ therapy slow aging?

It hasn't been shown to. Your cells use NAD+, and it's an active research area, but human studies of boosting it are small and short so far.

What should I ask before trying one?

What it's for, what evidence supports it in people like you, who makes the product, what the side effects are, and how you'll know if it worked.

What does it cost, and will insurance cover it?

These are almost always self-pay. Insurance may cover hyperbaric oxygen or plasma exchange only for approved medical reasons. Our guides on cost and insurance go deeper.

How do you decide which clinics appear on this page?

A clinic appears here when its own published material shows it offers this kind of testing at that location.

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